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Melanotan II is a synthetic cyclic lactam heptapeptide analogue of alpha-melanocyte-stimulating hormone, sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ (C₅₀H₆₉N₁₅O₉, 1024.2 g/mol, CAS 121062-08-6)