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One proposed strategy to address persistent symptoms has been to adjust LT4 dosing in order to maintain TSH levels in the lower part of the reference range (e.g., 0.4–2.0 mU/L), based on the hypothesis that doing so may more closely approximate the physiological set-point and potentially improve clinical outcomes

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That visibility helped normalize rituals around GLP-1 use, like self-injection and the purchase of low-cost copycat drugs online, Cohen says

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